SYNTHETIC METHODS .35. NITRILE ADDITIONS TO C,N-DIACYLIMINES - FORMATION OF 4-AMIDOOXAZOLES

被引：10

作者：

FISCHER, B ^{[1
]}

HASSNER, A ^{[1
]}

机构：

[1] BAR ILAN UNIV,DEPT CHEM,IL-52100 RAMAT GAN,ISRAEL

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 18期

关键词：

D O I：

10.1021/jo00305a015

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitriles are shown to react with C,N-diacylimines 2, generated in situ from 1 or 4 in the presence of Lewis acids, to produce 4-amidooxazoles 5 and 6 in good to excellent yield. Diamides are sometimes also produced. The reaction was followed by NMR spectroscopy, and mechanistic pathways are discussed. © 1990, American Chemical Society. All rights reserved.

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页码：5225 / 5229

页数：5

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