TOTAL SYNTHESIS OF MYXOVIRESCIN-B

被引：22

作者：

WILLIAMS, DR

MCGILL, JM

机构：

[1] Department of Chemistry, Indiana University, Bloomington

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 11期

关键词：

D O I：

10.1021/jo00298a016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A high convergent total synthesis of optically active myxovirescin B, a 28-membered macrolactam lactone (lc), is presented. Ring closure of the macrocycle was efficiently accomplished via an intramolecular Horner-Emmons reaction of the sensitive aldehydic phosphonate 18b. © 1990, American Chemical Society. All rights reserved.

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页码：3457 / 3459

页数：3

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