TREATMENT OF ADVANCED LOCALIZED PROSTATIC-CANCER BY ORCHIECTOMY, RADIOTHERAPY, OR COMBINED TREATMENT - A MEDICAL-RESEARCH-COUNCIL STUDY

被引：51

作者：

FELLOWS, GJ

CLARK, PB

BEYNON, LL

BOREHAM, J

KEEN, C

PARKINSON, MC

PETO, R

WEBB, JN

机构：

[1] GEN INFIRM,LEEDS LS1 3EX,W YORKSHIRE,ENGLAND

[2] NEW CROSS HOSP,WOLVERHAMPTON WV10 0QP,W MIDLANDS,ENGLAND

[3] RADCLIFFE INFIRM,OXFORD OX2 6HE,ENGLAND

[4] MIDDLESEX HOSP,LONDON W1,ENGLAND

[5] WESTERN GEN HOSP,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND

来源：

BRITISH JOURNAL OF UROLOGY | 1992年 / 70卷 / 03期

关键词：

D O I：

10.1111/j.1464-410X.1992.tb15736.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A total of 277 patients with apparently localised prostatic cancer (T2-T4 NXMO) were allocated at random to receive radiotherapy alone (88), orchiectomy alone (90) and combined therapy (99) between 1980 and 1985. The main outcome measures were survival, time to appearance of metastases and treatment of local disease progression by further transurethral resection. Orchiectomy, whether alone or with radiotherapy, produced a significant delay in detection of metastases when compared with radiotherapy alone. There were no statistically significant differences between the 3 treatment groups in local disease control or in overall survival.

引用

页码：304 / 309

页数：6

共 6 条

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