MECHANISM-BASED DESIGN, SYNTHESIS, AND IN-VITRO ANTIMALARIAL TESTING OF NEW 4-METHYLATED TRIOXANES STRUCTURALLY RELATED TO ARTEMISININ - THE IMPORTANCE OF A CARBON-CENTERED RADICAL FOR ANTIMALARIAL ACTIVITY

被引:178
作者
POSNER, GH
OH, CH
WANG, DS
GERENA, L
MILHOUS, WK
MESHNICK, SR
ASAWAMAHASADKA, W
机构
[1] WALTER REED ARMY MED CTR,WALTER REED ARMY INST RES,DIV EXPTL THERAPEUT,WASHINGTON,DC 20307
[2] UNIV MICHIGAN,SCH PUBL HLTH,DEPT EPIDEMIOL,ANN ARBOR,MI 48109
关键词
D O I
10.1021/jm00035a003
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
[No abstract available]
引用
收藏
页码:1256 / 1258
页数:3
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