CT-GUIDED STEREOTAXIC FIBRINOLYSIS OF SPONTANEOUS AND HYPERTENSIVE CEREBELLAR HEMORRHAGE - LONG-TERM RESULTS

被引:54
作者
MOHADJER, M
EGGERT, R
MAY, J
MAYFRANK, L
机构
[1] Klin. der Albert-Ludwigs Univ, Neurochirurgische Univ.-Klin., Abteilung Stereotaxie, D-7800 Freiburg
关键词
cerebellar hemorrhage; fibrinolysis; stereotaxis; timing of surgery; urokinase;
D O I
10.3171/jns.1990.73.2.0217
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The surgical indication for spontaneous cerebellar hemorrhage is not as controversial as the operative management of intracranial hemorrhage. Timing of the operation is crucial: intervening too early can produce an additional strain on the patient and an increased risk, while waiting too long to evacuate the hematoma can be fatal. This dilemma may be a factor in the relatively high mortality and morbidity rates following both operative and conservative treatment that have been reported in the literature (42.5% and 30%, respectively). In long-term studies on 14 patients, the authors have shown that stereotactic puncture and fibrinolysis for cerebellar hemorrhage is a valuable alternative to treatments used currently. The method consists of computerized tomography (CT)-guided stereotactic puncture and partial evacuation of the hematoma. After fibrinolysis with urokinase, the residual hematoma can be completely evacuated via a catheter introduced into the cavity of the hematoma. Only one of the 14 patients died in the direct postoperative phase; the remaining patients were enjoying a good to very good quality of life 6 months after the acute event. Two patients subsequently died as a result of pneumonia and cerebral infarction, respectively; both conditions were unrelated to the hemorrhage. The authors conclude that the CT-guided stereotactic method is simple, effective, and safe, and can be applied to patients of any age.
引用
收藏
页码:217 / 222
页数:6
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