SEPARATION OF HYDROXYBENZOIC ACIDS BY PACKED-COLUMN SUPERCRITICAL FLUID CHROMATOGRAPHY USING MODIFIED FLUIDS WITH VERY POLAR ADDITIVES

被引：45

作者：

BERGER, TA

DEYE, JF

机构：

[1] Hewlett-Packard, Avondale, PA, 19311

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 1991年 / 29卷 / 01期

关键词：

D O I：

10.1093/chromsci/29.1.26

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The polarity of compounds that can be separated by packed column supercritical fluid chromatography (SFC) can be extended to include mono-, di-, and trihydroxybenzoic acids without derivatization. The separations are accomplished by adding very polar additives like citric acid and trifluoroacetic acid to a modified mobile phase. Separations obtained using very polar additives are up to 10 times faster than those typically obtained with polymer-based ion exchange columns and an aqueous mobile phase.

引用

页码：26 / 30

页数：5

共 6 条

[1] NILE RED AS A SOLVATOCHROMIC DYE FOR MEASURING SOLVENT STRENGTH IN NORMAL LIQUIDS AND MIXTURES OF NORMAL LIQUIDS WITH SUPERCRITICAL AND NEAR CRITICAL FLUIDS [J].