INTRAARTERIAL 4-HYDROXYANISOLE CHEMOTHERAPY FOR LOCALLY RECURRENT MALIGNANT-MELANOMA - A REAPPRAISAL

被引：5

作者：

BELCHER, HJCR ^{[1
]}

NIZAM, M ^{[1
]}

ONEILL, TJ ^{[1
]}

机构：

[1] W NORWICH HOSP,DEPT PLAST SURG,NORWICH NR2 3TU,NORFOLK,ENGLAND

来源：

BRITISH JOURNAL OF PLASTIC SURGERY | 1992年 / 45卷 / 03期

关键词：

D O I：

10.1016/0007-1226(92)90078-C

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Ten female patients with recurrent cutaneous malignant melanoma (MM) confined to the lower limb were treated with 4-hydroxyanisole (4HA) infused intra-arterially. 10 g of 4HA was infused twice per day up to a maximum dose of 80 g. 4HA infusion caused significant alterations in liver function which precluded completion of the treatment regimen in all but two patients. No tumour regression was observed in any patient. We cannot recommend this technique for managing patients with recurrent cutaneous MM.

引用

页码：208 / 210

页数：3

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