COLLAGEN-CHITOSAN COMPOSITE MEMBRANES FOR CONTROLLED-RELEASE OF PROPRANOLOL HYDROCHLORIDE

被引：42

作者：

THACHARODI, D ^{[1
]}

RAO, KP ^{[1
]}

机构：

[1] CENT LEATHER RES INST,DIV BIOMAT,MADRAS 600020,TAMIL NADU,INDIA

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1995年 / 120卷 / 01期

关键词：

COMPOSITE MEMBRANE; COLLAGEN; CHITOSAN; PROPRANOLOL HYDROCHLORIDE;

D O I：

10.1016/0378-5173(94)00423-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Composite membranes consisting of collagen and chitosan in various proportions were prepared and characterized by Fourier transform infrared spectroscopy and equilibrium swelling studies. The permeability properties of these membranes for propranolol hydrochloride were studied and compared with those of collagen and chitosan membranes. The permeability properties of the composite membranes were found to depend on the concentration of collagen and chitosan in the membranes.

引用

页码：115 / 118

页数：4

共 7 条

[1]

Nakatsuka, Andrady, Permeability of vitamin B-12 in chitosan membranes, Effect of crosslinking and blending with poly(vinyl alcohol) on permeability, 44, pp. 17-28, (1992)

[2]

Panduranga Rao, Joseph, Collagen graft copolymers and their biomedical applications, Collagen, 3, pp. 63-85, (1988)

[3]

Shahabeddin, Damour, Berthod, Rousselle, Saintigny, Collombel, Reconstructed skin from co-cultured human keratinocytes and fibroblasts on chitosan crosslinked collagen-GAG matrix, J. Mater. Sci. Mater. Med., 2, pp. 222-226, (1991)

[4]

Stol, Poly(2-hydroxyethyl methacrylate)-collagen composites for biomedical applications, J. Bioact. Compat. Polym., 6, pp. 308-315, (1991)

[5]

Taravel, Domard, Relation between the physicochemical characteristics of collagen and its interactions with chitosan: 1, Biomaterials, 14, pp. 930-938, (1993)

[6]

Thacharodi, Panduranga Rao, Propranolol hydrochloride release behavior of crosslinked chitosan membranes, J. Chem. Tech. Biotechnol., 58, pp. 177-181, (1993)

[7]

Weiss, Elstow, Extraction isolation and characterization of neutral salt soluble type-V collagen from fetal calf skin, Collagen and Related Research, 3, pp. 181-194, (1983)

← 1 →