SPHINGOLIPIDS AND GLYCEROLIPIDS .1. CHEMICAL STRUCTURES AND IONOPHORETIC ACTIVITIES OF SOYA-CEREBROSIDE-I AND SOYA-CEREBROSIDE-II FROM SOYBEAN

被引：74

作者：

SHIBUYA, H ^{[1
]}

KAWASHIMA, K ^{[1
]}

SAKAGAMI, M ^{[1
]}

KAWANISHI, H ^{[1
]}

SHIMOMURA, M ^{[1
]}

OHASHI, K ^{[1
]}

KITAGAWA, I ^{[1
]}

机构：

[1] OSAKA UNIV, FAC PHARMACEUT SCI, 1-6 YAMADA OKA, SUITA, OSAKA 565, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1990年 / 38卷 / 11期

关键词：

fatty acid analysis; Glycine max; glycosphingolipid; ion-binding activity; ion-transport activity; ionophoretic activity; liquid; membrane apparatus; soya-cerebroside I; soya-cerebroside II; soybean;

D O I：

10.1248/cpb.38.2933

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two glycosphingolipids named soya-cerebrosides I and II were isolated from soybean, the seeds of Glycine max merrill (Leguminosae), and their chemical structures have been elucidated on the basis of physicochemical evidence and several chemical degradation reactions. By using a newly constructed liquid membrane-type apparatus (W-08) for measurement of ion-transport and ion-binding activities and by employing a method using human erythrocyte membranes for measurement of ion-permeability, it has been found that soya-cerebroside II exhibits ionophoretic activity for Ca2+ ion. © 1990, The Pharmaceutical Society of Japan. All rights reserved.

引用

页码：2933 / 2938

页数：6

共 32 条

[1] STRUCTURE OF MONENSIC ACID A NEW BIOLOGICALLY ACTIVE COMPOUND [J].

AGTARAP, A ;

CHAMBERLIN, JW ;

PINKERTON, M ;

STEINRAUF, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1967, 89 (22) :5737-+

[2]

CARTER HE, 1961, J LIPID RES, V2, P228

[3] ALKYL SUBSTITUTED AZA-MACROBICYCLIC POLYETHERS - HIGHLY EFFICIENT CATALYSTS IN 2-PHASE REACTIONS [J].

CINQUINI, M ;

MONTANARI, F .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1975, (10) :393-394

[4]

CLEMENT D, 1976, HETEROCYCLES, V5, P477

[5]

HAKOMORI SI, 1983, HDB LIPID RES, V3

[6]

HALLIDAY N, 1940, J BIOL CHEM, P132

[7] SPHINGOLIPID LONG CHAIN BASES [J].

KARLSSON, KA .

LIPIDS, 1970, 5 (11) :878-&

[8]

KAWANOTAKAHASHI Y, 1986, INT J OBESITY, V10, P293

[9]

KITAGAWA I, 1985, CHEM PHARM BULL, V33, P598

[10]

KITAGAWA I, 1989, CHEM PHARM BULL, V37, P1416, DOI 10.1248/cpb.37.1416

← 1 2 3 4 →