URINARY HYDROXYPROLINE EXCRETION IN CARCINOMA OF THE PROSTATE - COMPARISON OF 4 DIFFERENT MODES OF ASSESSMENT AND ITS ROLE AS A MARKER

被引:21
作者
MUNDY, AR
机构
[1] Department of Urology, Guy's Hospital, London
来源
BRITISH JOURNAL OF UROLOGY | 1979年 / 51卷 / 06期
关键词
D O I
10.1111/j.1464-410X.1979.tb03604.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Summary— Urinary hydroxyproline (HP) excretion has been estimated without prior dietary restriction in 33 patients with carcinoma of the prostate and expressed as either 24‐h HP output or as the hydroxyproline/creatinine (HP/Cr) ratio in a 24‐h urine sample, an early morning urine sample or a spot urine sample. The early morning urine hydroxyproline/creatinine ratio (EMU HP/Cr) appears to be the most accurate and avoids the disadvantages of formal dietary restriction and prolonged urine collection. The rest is useful in monitoring the response to treatment of a patient with bony metastatic disease and relapse of a patient when his tumour ceases to be hormone sensitive. Furthermore, changes in EMU HP/Cr occur earlier than changes in other clinical or investigative variables, giving the test predictive value. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码:570 / 574
页数:5
相关论文
共 16 条
  • [1] URINE HYDROXYPROLINE EXCRETION - MARKER OF BONE METASTASES IN PROSTATIC CARCINOMA
    BISHOP, MC
    FELLOWS, GJ
    [J]. BRITISH JOURNAL OF UROLOGY, 1977, 49 (07): : 711 - 716
  • [2] BONNADONNA G, 1966, N ENGL J MED, V275, P298
  • [3] URINARY HYDROXYPROLINE EXCRETION IN EARLY AND ADVANCED BREAST-CANCER - SEQUENTIAL STUDY
    CUSCHIERI, A
    [J]. BRITISH JOURNAL OF SURGERY, 1973, 60 (10) : 800 - 803
  • [4] RELEVANCE OF HYDROXYPROLINE EXCRETION TO BONE METASTASIS IN BREAST-CANCER
    GIELEN, F
    DEQUEKER, J
    DROCHMANS, A
    WILDIERS, J
    MERLEVEDE, M
    [J]. BRITISH JOURNAL OF CANCER, 1976, 34 (03) : 279 - 285
  • [5] GUZZO CE, 1969, CANCER, V24, P382, DOI 10.1002/1097-0142(196908)24:2<382::AID-CNCR2820240221>3.0.CO
  • [6] 2-S
  • [7] HYDROXYPROLINE EXCRETION IN MALIGNANT NEOPLASTIC DISEASE
    HOSLEY, HF
    TAFT, EG
    OLSON, KB
    GATES, S
    BEEBE, RT
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1966, 118 (06) : 565 - &
  • [8] KATZ FH, 1968, J LAB CLIN MED, V71, P65
  • [9] BONE SCINTISCANNING UPDATED
    LENTLE, BC
    RUSSELL, AS
    PERCY, JS
    SCOTT, JR
    JACKSON, FI
    [J]. ANNALS OF INTERNAL MEDICINE, 1976, 84 (03) : 297 - 303
  • [10] NEUMAN RE, 1950, J BIOL CHEM, V186, P549