PROLACTIN SECRETION FOLLOWING REPETITIVE SEIZURES

被引：30

作者：

MALKOWICZ, DE

LEGIDO, A

JACKEL, RA

SUSSMAN, NM

ESKIN, BA

HARNER, RN

机构：

[1] MED COLL PENN,DEPT NEUROL,PHILADELPHIA,PA 19129

[2] MED COLL PENN,DEPT OBSTET & GYNECOL,PHILADELPHIA,PA 19129

[3] MED COLL PENN,DEPT NEUROL,PHILADELPHIA,PA 19129

[4] HAHNEMANN UNIV,SCH MED,PHILADELPHIA,PA 19102

[5] EPILEPSY CTR BUCKS & MONTGOMERY COUNTIES,SELLERSVILLE,PA

[6] ST CHRISTOPHERS HOSP CHILDREN,NEUROL SECT,PHILADELPHIA,PA 19133

[7] BRISTOL MYERS SQUIBB CO,DEPT CENT NERVOUS SYST RES,WALLINGFORD,CT 06492

来源：

NEUROLOGY | 1995年 / 45卷 / 03期

关键词：

D O I：

10.1212/WNL.45.3.448

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied serum prolactin levels after 24 seizures occurring in eight subjects, Video-EEG intracranial monitoring confirmed temporal or frontal partial seizures, Seizure type, focus, and duration were similar for seizures with and without significant postictal prolactin elevations. The seizure-free interval (the time between seizures) varied considerably. Seizures occurring after longer seizure-free intervals (31.75 to 240 hours) showed robust prolactin responses, After shorter seizure-free intervals (1.07 to 25.42 hours), prolactin responses were reduced. This suggests that the amount of releasable prolactin is limited, depleted by seizures, or perhaps inhibited by prolactin feedback. Seizure-free intervals should be considered when interpreting prolactin levels.

引用

页码：448 / 452

页数：5

共 34 条

[1] SERUM PROLACTIN AND CORTISOL CONCENTRATIONS AFTER GRAND MAL SEIZURES [J].