CROSS-LINKING OF COLLAGEN IN THE X-LINKED EHLERS-DANLOS TYPE-V

被引：43

作者：

SIEGEL, RC

BLACK, CM

BAILEY, AJ

机构：

[1] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,LONDON W12 0HS,ENGLAND

[2] ARC,INST MEAT RES,BRISTOL BS18 7DY,AVON,ENGLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 88卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)91727-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The activity and antigenicity of the collagen crosslinking enzyme, lysyl oxidase, and the proportions of reducible crosslink in skin biopsies from Ehlers-Danlos Type V subjects were equivalent to those of control skin. These results reveal that both the potential for crosslinking, and the ability to form reducible crosslinks is present in Ehlers-Danlos syndrome Type V subjects, clearly demonstrating that the defect in this disorder is not due to a defective crosslinking mechanism. © 1979.

引用

页码：281 / 287

页数：7

共 18 条

[1]

BEIGHTON P, 1970, EHLERS DANLOS SYNDRO, P29

[2]

BLACK CM, 1978, ARTHRITIS RHEUM, V21, P545

[3] A SIMPLE EFFICIENT LIQUID SCINTILLATOR FOR COUNTING AQUEOUS SOLUTIONS IN A LIQUID SCINTILLATION COUNTER [J].