ANALYSIS OF SULFONAMIDES USING SUPERCRITICAL FLUID CHROMATOGRAPHY AND SUPERCRITICAL FLUID CHROMATOGRAPHY MASS-SPECTROMETRY

被引：38

作者：

PERKINS, JR

GAMES, DE

STARTIN, JR

GILBERT, J

机构：

[1] UNIV COLL SWANSEA, DEPT CHEM, MASS SPECTROMETRY RES UNIT, SWANSEA SA2 8PP, W GLAM, WALES

[2] MAFF, FOOD SCI UNIT, NORWICH, ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 540卷 / 1-2期

关键词：

D O I：

10.1016/S0021-9673(01)88813-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Packed-column supercritical fluid chromatography has been used for the separation of mixtures of sulphonamides on silica and amino-bonded stationary phases utilizing carbon dioxide with methanol modifier as the mobile phase. The effect of modifier concentration, column pressure and modifier identity on retention was also studied. Packed-column supercritical fluid chromatography-mass spectrometry (SFC-MS) of these mixtures utilizing both moving-belt and modified thermospray interfaces was also studied. The identification of sulphamethazine in a spiked porcine kidney extract was performed by SFC-MS using the moving-belt interface.

引用

页码：239 / 256

页数：18

共 25 条

[1] MONITORING OF VETERINARY DRUG RESIDUES BY A COMBINATION OF CONTINUOUS-FLOW TECHNIQUES AND COLUMN-SWITCHING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY .1. SULFONAMIDES IN EGG, MEAT AND MILK USING POST-COLUMN DERIVATIZATION WITH DIMETHYLAMINOBENZALDEHYDE
AERTS, MML
BEEK, WMJ
BRINKMAN, UAT
[J]. JOURNAL OF CHROMATOGRAPHY, 1988, 435 (01): : 97 - 112
[2] DETERMINATION OF SULFONAMIDE RESIDUES IN HONEYS BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY
BELLIARDO, F
[J]. JOURNAL OF APICULTURAL RESEARCH, 1981, 20 (01) : 44 - 48
[3] SUPERCRITICAL FLUID CHROMATOGRAPHIC AND SUPERCRITICAL FLUID CHROMATOGRAPHIC MASS-SPECTROMETRIC STUDIES OF SOME POLAR COMPOUNDS
BERRY, AJ
GAMES, DE
PERKINS, JR
[J]. JOURNAL OF CHROMATOGRAPHY, 1986, 363 (02): : 147 - 158
[4] PACKED-COLUMN SUPERCRITICAL FLUID CHROMATOGRAPHY-MASS SPECTROMETRY USING A THERMOSPRAY SOURCE IN THE FILAMENT-ON MODE
BERRY, AJ
GAMES, DE
MYLCHREEST, IC
PERKINS, JR
PLEASANCE, S
[J]. BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1988, 15 (02): : 105 - 109
[5] BERRY AJ, 1986, ANAL P, V23, P451
[6] IDENTIFICATION OF SULFONAMIDE DRUGS IN SWINE LIVER BY COLLISION-INDUCED DISSOCIATION MASS ANALYZED ION KINETIC-ENERGY SPECTROMETRY
BRUMLEY, WC
MIN, Z
MATUSIK, JE
ROACH, JAG
BARNES, CJ
SPHON, JA
FAZIO, T
[J]. ANALYTICAL CHEMISTRY, 1983, 55 (08) : 1405 - 1409
[7] RAPID QUALITATIVE IDENTIFICATION OF SULFONAMIDES BY MASS-SPECTROMETRY
DAVIS, R
HURST, DT
TAYLOR, AR
[J]. JOURNAL OF APPLIED CHEMISTRY AND BIOTECHNOLOGY, 1977, 27 (10): : 543 - 548
[8] SCREENING, CONFIRMATION, AND QUANTIFICATION OF SULFONAMIDE RESIDUES IN PIG-KIDNEY BY TANDEM MASS-SPECTROMETRY OF CRUDE EXTRACTS
FINLAY, EMH
GAMES, DE
STARTIN, JR
GILBERT, J
[J]. BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1986, 13 (11): : 633 - 639
[9] SUPERCRITICAL FLUID CHROMATOGRAPHY WITH SMALL PARTICLE DIAMETER PACKED-COLUMNS
GERE, DR
BOARD, R
MCMANIGILL, D
[J]. ANALYTICAL CHEMISTRY, 1982, 54 (04) : 736 - 740
[10] Haagsma N, 1987, Biomed Chromatogr, V2, P41, DOI 10.1002/bmc.1130020112

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