SYNTHESIS OF 2,4-DIMETHYLGLUTARIC ACID MONOESTERS VIA ENZYME-CATALYZED ASYMMETRIC ALCOHOLYSIS OF MESO-2,4-DIMETHYLGLUTARIC ANHYDRIDE

被引：25

作者：

OZEGOWSKI, R

KUNATH, A

SCHICK, H

机构：

[1] Centre of Selective Organic Synthesis, D(O)- 1199 Berlin-Adlershof

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(00)80177-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

1-(2-Methylpropyl) 5-hydrogen (2R,4S)2,4-dimethylpentanedioate with an enantiomeric excess of 90 % was obtained in a yield of 72 % from meso-2,4-dimethylpentanedioic anhydride and 2-methylpropanol by an asymmetric alcoholysis catalyzed by the lipase from Candida sp. 382.

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页码：695 / 698

页数：4

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