THE RAPID DETECTION OF UNKNOWN MUTATIONS IN NUCLEIC-ACIDS

被引:308
作者
GROMPE, M [1 ]
机构
[1] OREGON HLTH SCI UNIV,DEPT PEDIAT,PORTLAND,OR 97201
关键词
D O I
10.1038/ng1093-111
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The task of identifying mutations in nucleic acid sequences is a vital component of research in mammalian genetics. With the advent of the polymerase chain reaction, several useful mutation detection techniques have evolved in recent years. The different methods have complementing strengths and a suitable procedure for virtually any experimental situation is now available.
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页码:111 / 117
页数:7
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