RECURRENT URINARY-TRACT INFECTIONS IN MEN - CHARACTERISTICS AND RESPONSE TO THERAPY

被引：84

作者：

SMITH, JW

JONES, SR

REED, WP

TICE, AD

DEUPREE, RH

KAIJSER, B

机构：

[1] VET ADM HOSP, PORTLAND, OR 97207 USA

[2] VET ADM HOSP, ALBUQUERQUE, NM 87108 USA

[3] VET ADM MED CTR, PROVIDENCE, RI USA

[4] GOTENBURG UNIV, INST MED MICROBIOL, S-41124 GOTHENBURG, SWEDEN

[5] COOPERAT STUDIES PROGRAM COORDINATING CTR, W HAVEN, CT USA

来源：

ANNALS OF INTERNAL MEDICINE | 1979年 / 91卷 / 04期

关键词：

D O I：

10.7326/0003-4819-91-4-544

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

All men with recurrent urinary tract infections entered into a study had a positive antibody-coated bacteria test, and 52% had evidence for prostate infection. Escherichia coli infection was present in 74% and urinary tract symptoms in 57% of those randomized. Thirty-eight patients were randomized in a double-blind clinical trial to receive either 10 days of treatment with trimethoprim/sulfamethoxazole or a 12-wk course of the drug. The cure rate in patients receiving 12 weeks of therapy (nine of 15) was higher than that in patients receiving a single 10-day course (three of 15); difference was marginally significant (P = 0.06). Recurrences were usually with the same organism, and most (78%) occurred within 4 weeks of discontinuing therapy. This study indicates that a standard 10-day course of therapy usually fails to cure men with recurrent urinary tract infections with a positive antibody-coated bacteria test.

引用

页码：544 / 548

页数：5