SIMILARITY OF DNA FINGERPRINTS DUE TO CHANCE AND RELATEDNESS

被引：230

作者：

LI, CC

WEEKS, DE

CHAKRAVARTI, A

机构：

[1] Department of Human Genetics, Graduate School of Public Health, University of Pittsburg, PA

来源：

HUMAN HEREDITY | 1993年 / 43卷 / 01期

关键词：

DNA FINGERPRINTS; COEFFICIENT OF RELATIONSHIP; RELATEDNESS; POPULATION GENETICS;

D O I：

10.1159/000154113

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance and relatedness. From these results, the degree of similarity due to relatedness alone may be calculated.

引用

页码：45 / 52

页数：8

共 17 条

[1]

CHAKRAVARTI A, 1989, AM J HUM GENET, V44, P639

[2]

CHAKRAVARTI A, 1991, HUM GENET, V87, P721

[3] EXCLUSION OF A MAN CHARGED WITH MURDER BY DNA FINGERPRINTING [J].