GENETIC-CONTROL OF BACTERIAL SUICIDE - REGULATION OF THE INDUCTION OF PBSX IN BACILLUS-SUBTILIS

被引：49

作者：

MCDONNELL, GE ^{[1
]}

WOOD, H ^{[1
]}

DEVINE, KM ^{[1
]}

MCCONNELL, DJ ^{[1
]}

机构：

[1] UNIV DUBLIN TRINITY COLL, DEPT GENET, DUBLIN 2, IRELAND

来源：

JOURNAL OF BACTERIOLOGY | 1994年 / 176卷 / 18期

关键词：

D O I：

10.1128/JB.176.18.5820-5830.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

PBSX is a phage-like bacteriocin (phibacin) of Bacillus subtilis 168. Bacteria carrying the PBSX genome are induced by DNA damaging agents to lyse and produce PBSX particles. The particles cannot propagate the PBSX genome. The particles produced by this suicidal response kill strains nonlysogenic for PBSX. A 5.2-kb region which controls the induction of PBSX has been sequenced. The genes identified include the previously identified repressor gene xre and a positive control factor gene, pcf. Pcf is similar to known sigma factors and acts at the late promoter P-L, which has been located distal to pcf. The first two genes expressed from the late promoter show homology to genes encoding the subunits of phage terminases.

引用

页码：5820 / 5830

页数：11

共 43 条

[1] MOLECULAR-CLONING AND CHARACTERIZATION OF 2 GENES ENCODING SIGMA FACTORS THAT DIRECT TRANSCRIPTION FROM A BACILLUS-THURINGIENSIS CRYSTAL PROTEIN GENE PROMOTER [J].

ADAMS, LF ;

BROWN, KL ;

WHITELEY, HR .

JOURNAL OF BACTERIOLOGY, 1991, 173 (12) :3846-3854

[2] BASIC LOCAL ALIGNMENT SEARCH TOOL [J].

ALTSCHUL, SF ;

GISH, W ;

MILLER, W ;

MYERS, EW ;

LIPMAN, DJ .

JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) :403-410

[3] THE SPOIIJ GENE, WHICH REGULATES EARLY DEVELOPMENTAL STEPS IN BACILLUS-SUBTILIS, BELONGS TO A CLASS OF ENVIRONMENTALLY RESPONSIVE GENES [J].

ANTONIEWSKI, C ;

SAVELLI, B ;

STRAGIER, P .

JOURNAL OF BACTERIOLOGY, 1990, 172 (01) :86-93

[4] GENE ENCODING THE SIGMA-37 SPECIES OF RNA-POLYMERASE SIGMA-FACTOR FROM BACILLUS-SUBTILIS [J].

BINNIE, C ;

LAMPE, M ;

LOSICK, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (16) :5943-5947

[5]

BLACK LW, 1989, ANNU REV MICROBIOL, V43, P267, DOI 10.1146/annurev.micro.43.1.267

[6] PROPHAGE MUTATION CAUSING HEAT INDUCIBILITY OF DEFECTIVE BACILLUS-SUBTILIS BACTERIOPHAGE PBSX [J].

BUXTON, RS .

JOURNAL OF VIROLOGY, 1976, 20 (01) :22-28

[7] SELECTION OF BACILLUS-SUBTILIS-168 MUTANTS WITH DELETIONS OF THE PBSX PROPHAGE [J].

BUXTON, RS .

JOURNAL OF GENERAL VIROLOGY, 1980, 46 (FEB) :427-437

[8] THE DEVELOPMENTAL FATE OF S-COELICOLOR HYPHAE DEPENDS UPON A GENE-PRODUCT HOMOLOGOUS WITH THE MOTILITY SIGMA-FACTOR OF B-SUBTILIS [J].

CHATER, KF ;

BRUTON, CJ ;

PLASKITT, KA ;

BUTTNER, MJ ;

MENDEZ, C ;

HELMANN, JD .

CELL, 1989, 59 (01) :133-143

[9]

COHEN SN, 1972, MOL GEN GENET, V167, P251

[10]

CONTENTE S, 1979, P NATL ACAD SCI USA, V69, P2110

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