EFFECT OF CANDIDA MORPHOLOGY ON AMPHOTERICIN-B SUSCEPTIBILITY

被引:11
作者
NUGENT, KM
COUCHOT, KR
GRAY, LD
机构
[1] UNIV TEXAS, HLTH SCI CTR, DEPT MED, TYLER, TX 75710 USA
[2] UNIV TEXAS, HLTH SCI CTR, DEPT CELL BIOL, TYLER, TX 75710 USA
关键词
D O I
10.1128/AAC.31.2.335
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We showed that brief exposures to amphotericin B (AmB) inhibited the induction of new Candida germ tubes and the lengthening of partially induced germ tubes. Blastoconidia with germ tubes were more susceptible to AmB killing, and this varied directly with the induction period and the AmB exposure period. AmB did not preferentially affect germ tube adherence to fibrin matrices.
引用
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页码:335 / 336
页数:2
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