TOPOGRAPHY OF GLYCOSYLATION REACTIONS IN THE ENDOPLASMIC-RETICULUM

被引：196

作者：

ABEIJON, C

HIRSCHBERG, CB

机构：

[1] Department of Biochemistry and Molecular Biology, University of Massachusetts Medical Center, Worcester

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 01期

关键词：

D O I：

10.1016/0968-0004(92)90424-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A variety of distinct protein glycosylation reactions occur in the endoplasmic reticulum (ER) of eukaryotic cells. In some instances, both the proteins to be glycosylated and the precursor sugar donors must be translocated across the membrane from the cytoplasm to the lumen of the ER. Elucidation of the individual steps in each of the glycosylation pathways has revealed the topographic complexity of these reactions.

引用

页码：32 / 36

页数：5

共 36 条

[1]

ABEIJON C, 1990, J BIOL CHEM, V265, P14691

[2] INTRINSIC MEMBRANE-GLYCOPROTEINS WITH CYTOSOL-ORIENTED SUGARS IN THE ENDOPLASMIC-RETICULUM [J].