ANTIBIOTIC PEPTIDES AS MEDIATORS OF INNATE IMMUNITY

被引：317

作者：

ZASLOFF, M ^{[1
]}

机构：

[1] UNIV PENN,SCH MED,PHILADELPHIA,PA 19104

来源：

CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 01期

关键词：

D O I：

10.1016/0952-7915(92)90115-U

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antibiotic peptides are widely distributed in nature. Almost all function as membrane-active agents, disrupting target-cell permeability. Several exhibit a striking selectivity for single-celled microbes over metazoan cells, and as such are amongst the simplest components of the animal's defensive system, which distinguishes environmental microbes from 'self.

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页码：3 / 7

页数：5

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