REGIOSELECTIVE LIPASE-MEDIATED ACYLATION-DEACYLATION IN THIADIAZINE DIACYCLONUCLEOSIDES

被引：12

作者：

ESTEBAN, AI ^{[1
]}

JUANES, O ^{[1
]}

MARTINEZ, A ^{[1
]}

CONDE, S ^{[1
]}

机构：

[1] CSIC, INST QUIM MED, E-28006 MADRID, SPAIN

来源：

TETRAHEDRON | 1994年 / 50卷 / 48期

关键词：

D O I：

10.1016/S0040-4020(01)85694-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first thiadiazine acyclonucleosides has been prepared, and so acyclic glycosylation of the SO2 analog of 6-methyluracil has been achieved. Regioselective deprotection of thiadiazine diacyclonucleoside has been performed by a combined strategy of enzyme-catalyzed hydrolysis-acylation.

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收藏

页码：13865 / 13870

页数：6

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