TREATMENT WITH LENOGRASTIM (GLYCOSYLATED RECOMBINANT HUMAN GRANULOCYTE-COLONY-STIMULATING FACTOR) AND ORTHOTOPIC LIVER-TRANSPLANTATION FOR GLYCOGEN-STORAGE-DISEASE TYPE-IB

被引：26

作者：

LACHAUX, A

BOILLOT, O

STAMM, D

CANTERINO, I

DUMONTET, C

REGNIER, F

FLORET, D

HERMIER, M

机构：

[1] Dept. of Pediatrics (Liver Transplantation Unit, Pediatric Intensive Care Unit, and Pediatric Radiol, Hôpital E. Herrlott, Lyon

来源：

JOURNAL OF PEDIATRICS | 1993年 / 123卷 / 06期

关键词：

D O I：

10.1016/S0022-3476(05)80403-2

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A 7 1/2-year-old patient with glycogenosis type lb had chronic neutropenia, recurrent bacterial infections, and severe hypoglycemia in spite of continuous nasogastric feeding. She was treated with lenograstim (glycosylated recombinant human granulocyte colony-stimulating factor) and orthotopic liver transplantation. Absolute neutrophil counts and platelet counts rapidly reached normal values, and infectious episodes were reduced. She resumed oral feeding after transplantation and had no subsequent hypoglycemic episodes.

引用

页码：1005 / 1008

页数：4

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