CHANGES IN GLYCOLYSIS OF RAT THYMOCYTES AFTER A WHOLE-BODY X-IRRADIATION

被引：17

作者：

YAMADA, T

OHYAMA, H

KUMATORI, T

MINAKAMI, S

机构：

[1] National Institute of Radiological Sciences, Chiba

[2] Department of Biochemistry, Kyushu University School of Medicine, Fukuoka

来源：

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY AND RELATED STUDIES IN PHYSICS CHEMISTRY AND MEDICINE | 1969年 / 15卷 / 06期

关键词：

D O I：

10.1080/09553006914550791

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The aerobic production of lactate by suspensions of thymocytes prepared from irradiated rats was considerably increased in the early phase after a whole-body x-irradiation with 400 R. Intracellular concentrations of intermediates and co-factors of glycolysis were measured at various times up to 6 hours after the irradiation. Fructose-1,6-diphosphate showed a remarkable increase in the cells of rats killed immediately after the exposure. The changes in the levels of intermediates suggest the enhanced activity of phosphofructokinase in thymocytes after whole-body irradiation, as previously observed following in vitro irradiation. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：497 / &

共 23 条

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