SELECTIVE INHIBITORY EFFECT OF PORCINE FOLLICULAR-FLUID ON FOLLICLE-STIMULATING HORMONE-SECRETION IN ANTERIOR-PITUITARY CELLS IN CULTURE

被引：37

作者：

LAGACE, L

LABRIE, F

LORENZEN, J

SCHWARTZ, NB

CHANNING, CP

机构：

[1] CTR HOSP UNIV LAVAL, MRC, MOLEC ENDOCRINOL GRP, QUEBEC CITY G1V 4G2, QUEBEC, CANADA

[2] NORTHWESTERN UNIV, DEPT BIOL SCI, EVANSTON, IL 60201 USA

[3] UNIV MARYLAND, SCH MED, DEPT PHYSIOL, BALTIMORE, MD 21201 USA

来源：

CLINICAL ENDOCRINOLOGY | 1979年 / 10卷 / 04期

关键词：

D O I：

10.1111/j.1365-2265.1979.tb02095.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Incubation of rat anterior pituitary cells in culture with porcine follicular fluid (treated with charcoal to remove steroids) led to a marked inhibition of spontaneous FSH release while no effect was observed on basal LH secretion. The inhibitory effect of follicular fluid was, however, less specific on LHRH‐induced gonadotropin release. Although more potent on FSH than LH release, a significant inhibition of LH release induced by the neurohormone was also observed. This inhibitory activity is mainly associated with material of MW 10000 daltons. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：401 / 405

页数：5

共 16 条

[1]

BAKER HWG, 1976, BIOL REPROD, V14, P511

[2] ROLE OF ADRENAL AND OVARIAN STEROIDS IN CONTROL OF SERUM LH AND FSH [J].