ENZYMATIC ESTERIFICATION OF 3-HYDROXYBUTYRIC ACID

被引：9

作者：

CHATTOPADHYAY, S ^{[1
]}

MAMDAPUR, VR ^{[1
]}

机构：

[1] BHABHA ATOM RES CTR,DIV BIOORGAN,MOD LAB,BOMBAY 400085,INDIA

来源：

BIOTECHNOLOGY LETTERS | 1993年 / 15卷 / 03期

关键词：

D O I：

10.1007/BF00128313

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Candida cylindracea lipase catalysed esterification of (+/-)-3-hydroxybutyric acid (1) with n-butanol was studied in different solvents. This provided an alternative preparative method for the versatile chiron. butyl (S)-3-hydroxybutyrate (2) via kinetic resolution of (+)-1. With toluene as the reaction medium the enantioselection was found to be excellent for 2 and moderate for the resolved acid (1).

引用

页码：245 / 250

页数：6

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