INCREASE OF CELL-SURFACE HYALURONIC-ACID DURING AGING IN HUMAN-LIVER CELLS

被引：5

作者：

BERNARD, B

FONT, J

AUBERY, M

BAFFET, G

GUILLOUZO, A

机构：

[1] FAC MED PARIS, INSERM, U 180, RECH BIOL & PATHOL MOLEC GLYCOPROTEINES GRP, F-75006 PARIS, FRANCE

[2] HOP PONTCHAILLOU, INSERM, U 49, UNITE RECH HEPATOL, F-35011 RENNES, FRANCE

来源：

MECHANISMS OF AGEING AND DEVELOPMENT | 1982年 / 19卷 / 03期

关键词：

D O I：

10.1016/0047-6374(82)90055-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Fetal and newborn human liver cells exhibit 2 classes of Ricinus communis lectin binding site in the early passages; these cells at the late passages and adult cells have only 1 class of binding site. Hyaluronidase treatment of both fetal and newborn old cells and adult cells results in recovery of the 2 classes of binding site and in release of higher amounts of hyaluronic acid. Increased hyaluronic acid might play an important role in age-related cell membrane changes.

引用

页码：211 / 216

页数：6

共 11 条

[1] CHANGES IN RICINUS-COMMUNIS LECTIN BINDING TO THE CELL-SURFACE OF HUMAN-LIVER CELLS IN CULTURE - THE RELATIONSHIP BETWEEN INVITRO CELLULAR AGING AND THE AGE OF THE DONOR [J].