THE 1ST ENANTIOSELECTIVE SYNTHESES OF PURE R-ISOPROTERENOL AND S-ISOPROTERENOL

被引：70

作者：

COREY, EJ

LINK, JO

机构：

[1] Department of Chemistry, Harvard University, Cambridge

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)94578-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and highly selective synthetic route to either R- or S-isoproterenol (1) is described which employs a robot-like catalytic molecule to establish chirality, and readily provides these important therapeutic agents in enantiomerically pure form. © 1990.

引用

页码：601 / 604

页数：4

共 17 条

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[4] DUAL BINDING MODES TO THE RECEPTOR FOR PLATELET ACTIVATING FACTOR (PAF) OF ANTI-PAF TRANS-2,5-DIARYLFURANS
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[5] AN EFFICIENT AND CATALYTICALLY ENANTIOSELECTIVE ROUTE TO (S)-(-)-PHENYLOXIRANE
COREY, EJ
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[6] DIISOPROPYLSILYL DITRIFLATE AND DI-TERT-BUTYLSILYL DITRIFLATE - NEW REAGENTS FOR THE PROTECTION OF DIOLS
COREY, EJ
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[7] ENANTIOSELECTIVE ROUTE TO A KEY INTERMEDIATE IN THE TOTAL SYNTHESIS OF GINKGOLIDE-B
COREY, EJ
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[J]. TETRAHEDRON LETTERS, 1988, 29 (26) : 3201 - 3204
[8] HIGHLY ENANTIOSELECTIVE BORANE REDUCTION OF KETONES CATALYZED BY CHIRAL OXAZABOROLIDINES - MECHANISM AND SYNTHETIC IMPLICATIONS
COREY, EJ
BAKSHI, RK
SHIBATA, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (18) : 5551 - 5553
[9] A STABLE AND EASILY PREPARED CATALYST FOR THE ENANTIOSELECTIVE REDUCTION OF KETONES - APPLICATIONS TO MULTISTEP SYNTHESES
COREY, EJ
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SHIBATA, S
CHEN, CP
SINGH, VK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (25) : 7925 - 7926
[10] COREY EJ, 1989, 31ST P NAT ORG S, P1

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