DRUG ANALYSIS FOR CONTROL PURPOSES IN FORENSIC TOXICOLOGY, WORKPLACE TESTING, SPORTS MEDICINE AND RELATED AREAS

被引:12
作者
CHRISTOPHERSEN, AS
MORLAND, J
机构
[1] National Institute of Forensic Toxicology, Oslo, N-0320, P.O. Box 16, Gaustad
来源
PHARMACOLOGY & TOXICOLOGY | 1994年 / 74卷 / 4-5期
关键词
D O I
10.1111/j.1600-0773.1994.tb01099.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This MiniReview describes the present guidelines for drug testing in forensic toxicology, workplace testing and doping control of athletes. Such guidelines are established to secure the chain of custody, from sample collection through analysis with screening, confirmation methods and interpretation, to the final report of results. Specifications for good laboratory practice, facility maintenance and quality assurance programs are described. The advantages and limitation of immunological drug assays and the necessity of specific chromatographic confirmation methods are discussed. Tle importance of correct interpretation of positive test results is illustrated. The effect of drug testing on the prevalence of drug abuse, accident rates and effectivity at the workplace is discussed.
引用
收藏
页码:202 / 210
页数:9
相关论文
共 54 条
  • [1] SCREENING FOR DRUGS OF ABUSE WITH THE ROCHE ONTRAK ASSAYS
    ARMBRUSTER, DA
    KROLAK, JM
    [J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1992, 16 (03) : 172 - 175
  • [2] BECK O, 1992, CLIN CHEM, V38, P271
  • [3] BOND GD, 1990, J ANAL TOXICOL, V14, P389
  • [4] CAPLAN YH, 1989, J FORENSIC SCI, V34, P1417
  • [5] CHAMBERLAIN RT, 1989, J FORENSIC SCI, V34, P1477
  • [6] CHRISTOPHERSEN A S, 1991, Tidsskrift for den Norske Laegeforening, V111, P3300
  • [7] TETRAHYDROCANNABINOL STABILITY IN WHOLE-BLOOD - PLASTIC VERSUS GLASS CONTAINERS
    CHRISTOPHERSEN, AS
    [J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1986, 10 (04) : 129 - 131
  • [8] INTERFERENCE WITH ANALYSIS OF AMPHETAMINE IN BLOOD BY N-ETHYLBENZENAMINE FROM RUBBER SEPTUMS
    CHRISTOPHERSEN, AS
    BUGGE, A
    DAHLIN, E
    MORLAND, J
    WETHE, G
    [J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1988, 12 (03) : 147 - 149
  • [9] CLARK HW, 1990, WESTERN J MED, V152, P514
  • [10] PASSIVE INHALATION OF MARIJUANA SMOKE - URINALYSIS AND ROOM AIR LEVELS OF DELTA-9-TETRAHYDROCANNABINOL
    CONE, EJ
    JOHNSON, RE
    DARWIN, WD
    YOUSEFNEJAD, D
    MELL, LD
    PAUL, BD
    MITCHELL, J
    [J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1987, 11 (03) : 89 - 96