SERUM AND URINARY MANGANESE LEVELS IN PATIENTS WITH PARKINSONS-DISEASE

被引：18

作者：

JIMENEZJIMENEZ, FJ

MOLINA, JA

AGUILAR, MV

ARRIETA, FJ

JORGESANTAMARIA, A

CABRERAVALDIVIA, F

AYUSOPERALTA, L

RABASA, M

VAZQUEZ, A

GARCIAALBEA, E

MARTINEZPARA, MC

机构：

[1] HOSP PRINCIPE ASTURIAS, DEPT NEUROL, ALCALA DE HENARES, SPAIN

[2] HOSP DOCE OCTUBRE, DEPT NEUROL, MADRID, SPAIN

[3] UNIV SAN CARLOS, DEPT NEUROL, MADRID, SPAIN

[4] UNIV ALCALA DE HENARES, FAC PHARM, DEPT NUTR & BROMATOL, MADRID, SPAIN

来源：

ACTA NEUROLOGICA SCANDINAVICA | 1995年 / 91卷 / 05期

关键词：

PARKINSONS DISEASE; MANGANESE; CHROMIUM; COBALT; SERUM LEVELS; URINARY EXCRETION;

D O I：

10.1111/j.1600-0404.1995.tb07014.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To elucidate the possible role of manganese in the risk of developing Parkinson's disease (PD), we compared serum levels of manganese, and 24-h manganese excretion by urine in 29 PD patients and in 27 matched controls. We also measured chromium and cobalt in the same samples. All these values did not differ significantly between the groups, they were not influenced by antiparkinsonian drugs, and they did not correlate with age, age at onset and duration of the PD, scores of the Unified PD Rating Scale or the Hoehn and Yahr staging in the PD group. These results might suggest that serum levels and urinary excretion of manganese are apparently unrelated to the risk of developing PD.

引用

页码：317 / 320

页数：4

共 41 条

[1] BRAIN PEROXIDASE AND CATALASE IN PARKINSON DISEASE [J].