I-123 MIBG SCINTIGRAPHY IN ADULTS - A REPORT OF CLINICAL-EXPERIENCE

被引:28
作者
ELGAZZAR, AH [1 ]
GELFAND, MJ [1 ]
WASHBURN, LC [1 ]
CLARK, J [1 ]
NAGARAJ, N [1 ]
CUMMINGS, D [1 ]
HUGHES, J [1 ]
MAXON, HR [1 ]
机构
[1] CHILDRENS HOSP MED CTR,BOSTON,MA 02115
关键词
D O I
10.1097/00003072-199502000-00011
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Thirty-one adult patients with clinical findings suggestive of pheochromocytoma were studied with I-123 MIBG. All patients had images obtained at 24 and 48 hours. Five patients had abnormal uptake proved to be because of I-123 MIBG avid tumors. The remaining 26 patients had no proven tumors and showed physiologic uptake in various organs. The 24-hour images were of high quality. In all cases, the 48-hour images contributed no significant additional information. Only in 1 patient did the 48-hour image add some certainty. Physiologic uptake was seen in the salivary glands, liver, G.I. tract, and urinary bladder in all patients (100%). Uptake was also observed in the lung and heart (90%), normal adrenal glands (32%), thyroid (29%), spleen (23%) uterus (13%), and neck muscles (6%). The authors' experience indicates that I-123 MIBG gives superior images compared to the previously used I-131 MIBG, that the optimum imaging time for adults is 18-24 hours, and that normal distribution patterns including uterine and neck muscle uptake should be familiar to physicians interpreting the studies.
引用
收藏
页码:147 / 152
页数:6
相关论文
共 28 条
[1]  
BENZO J, 1986, CLIN NUCL MED, V11, P860
[2]  
BOMANJI J, 1987, J NUCL MED, V28, P973
[3]  
BOMANJI J, 1987, J NUCL MED, V28, P319
[4]  
BOMANJI J, 1987, J NUCL MED, V28, P1907
[5]  
BONNIN F, 1994, J NUCL MED, V35, P803
[6]   MULTIPLE EXTRAADRENAL AND THORACIC PHEOCHROMOCYTOMAS [J].
BRAEDEL, HU ;
LINDINGER, A ;
BERBERICH, R ;
SCHINDLER, E ;
CRISPLINDGREN, N .
UROLOGY, 1986, 28 (02) :95-99
[7]   COMPARISON OF IODOBENZYLGUANIDINE IMAGING WITH COMPUTED-TOMOGRAPHY IN LOCATING PHEOCHROMOCYTOMA [J].
CHATAL, JF ;
CHARBONNEL, B .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1985, 61 (04) :769-772
[8]  
FELDMAN JM, 1986, J NUCL MED, V27, P1691
[9]   COMPLEMENTARY ROLES OF CT AND I-131-MIBG SCINTIGRAPHY IN DIAGNOSING PHEOCHROMOCYTOMA [J].
FRANCIS, IR ;
GLAZER, GM ;
SHAPIRO, B ;
SISSON, JC ;
GROSS, BH .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1983, 141 (04) :719-725
[10]  
GELFAND MJ, 1986, J NUCL MED, V27, P1800