PATHOLOGY OF HEPATITIS-C VIRUS-INFECTION

被引：50

作者：

DHILLON, AP ^{[1
]}

DUSHEIKO, GM ^{[1
]}

机构：

[1] UNIV LONDON, ROYAL FREE HOSP, SCH MED, DEPT MED, LONDON NW3 2PF, ENGLAND

来源：

HISTOPATHOLOGY | 1995年 / 26卷 / 04期

关键词：

HEPATITIS C VIRUS (HCV); HEPATITIS; CIRRHOSIS; CARCINOMA; GENOTYPE; IMMUNITY;

D O I：

10.1111/j.1365-2559.1995.tb00191.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

This paper reviews our current knowledge of hepatitis C virus, its structure, epidemiology and pathological effects in man. The histopathological features of acute and chronic hepatitis due to hepatitis C virus are detailed and illustrated. The possible pathogenetic mechanisms involved in the liver injury are outlined and the significance of genotypic subtypes of the virus and of host genetic predisposition in relation to the liver injury and the response to therapy are summarized.

引用

页码：297 / 309

页数：13

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