PLANT ANTITUMOR AGENTS .2 STRUCTURE OF 2 NEW ALKALOIDS FROM CAMPTOTHECA ACUMINATA

被引：108

作者：

WANI, MC

WALL, ME

机构：

[1] Research Triangle Institute, Research Triangle Park

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 05期

关键词：

D O I：

10.1021/jo01257a036

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Further fractionation of C. acuminata has yielded two new alkaloids, hydroxycamptothecin (2) and methoxycamptothecin (3). The former could be methylated to give a methyl ether identical with 3. In order to establish the position of the hydroxyl group in ring A, nmr spectra of deuterated methoxycamptothecin and of the model compounds 7-10 have been obtained. The syntheses of model compounds have been described. © 1969, American Chemical Society. All rights reserved.

引用

页码：1364 / &

共 15 条

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