EXOCYCLIC BROMINATION OF N-SUBSTITUTED BETA-LACTAM AND GAMMA-LACTAM

被引：6

作者：

EASTON, CJ

PITT, MJ

机构：

[1] Department of Organic Chemistry, University of Adelaide, Adelaide, SA 5001

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(00)97425-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective halogenation of the N-susbtituted lactams (3a)-(3d) affords the corresponding exocyclic bromides (4a)-(4d). The procedure provides a novel alternative route to N-(α-haloalkyl)-substituted lactams, which are of particular interest in the synthesis of β-lactam antibiotics. © 1990.

引用

页码：3471 / 3474

页数：4

共 15 条

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