RESPONSE TO AUTOIMMUNE ENTEROPATHY TO CYCLOSPORINE-A THERAPY

被引：42

作者：

SANDERSON, IR

PHILLIPS, AD

SPENCER, J

WALKERSMITH, JA

机构：

[1] UNIV COLL & MIDDLESEX SCH MED,DEPT HISTOPATHOL,LONDON,ENGLAND

[2] QUEEN ELIZABETH HOSP CHILDREN,ACAD UNIT PAEDIAT GASTROENTEROL,LONDON E2 8PS,ENGLAND

来源：

GUT | 1991年 / 32卷 / 11期

关键词：

D O I：

10.1136/gut.32.11.1421

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Small bowel enteropathies that are associated with an autoimmune process are often resistant to treatment. Two children with autoimmune enteropathy were treated with cyclosporin A for eight months. Both improved, as assessed by growth, small intestinal mucosal morphology, and carbohydrate absorption. Cyclosporin A is useful in the treatment of autoimmune enteropathy. This report also suggests that T cell activation (which is suppressed by cyclosporin A) is important in the pathogenesis of this condition.

引用

页码：1421 / 1425

页数：5

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