RENIN AND ALDOSTERONE LEVELS AND HYPERTENSION FOLLOWING ENVENOMATION IN HUMANS BY THE YELLOW SCORPION LEIURUS-QUINQUESTRIATUS

被引：25

作者：

GUERON, M ^{[1
]}

ILIA, R ^{[1
]}

SHAHAK, E ^{[1
]}

SOFER, S ^{[1
]}

机构：

[1] BEN GURION UNIV NEGEV, SOROKA MED CTR, DIV PEDIAT, PEDIAT INTENS CARE UNIT, IL-84101 BEER SHEVA, ISRAEL

来源：

TOXICON | 1992年 / 30卷 / 07期

关键词：

D O I：

10.1016/0041-0101(92)90010-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Renin activity and aldosterone blood levels were measured in ten patients following scorpion envenomation by the scorpion Leiurus quinquestriatus. All patients were hypertensive on admission, with clinical signs of systemic intoxication. The blood renin and aldosterone levels were elevated in all ten patients. The observation of high blood pressure and elevated levels of renin suggests that in addition to increased circulating catecholamines following scorpion envenomation, sympathetically induced renin release may play an important role in the pathogenesis of hypertension. This observation re-emphasizes the importance of afterload reduction in the treatment of the cardiovascular manifestations of scorpion envenomation.

引用

页码：765 / 767

页数：3

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