EVIDENCE THAT A-BETA-42 IS THE REAL CULPRIT IN ALZHEIMERS-DISEASE

[1] RELEASE OF EXCESS AMYLOID BETA-PROTEIN FROM A MUTANT AMYLOID BETA-PROTEIN PRECURSOR [J]. SCIENCE, 1993, 259 (5094) : 514 - 516

[2] MUTATION OF THE BETA-AMYLOID PRECURSOR PROTEIN IN FAMILIAL ALZHEIMERS-DISEASE INCREASES BETA-PROTEIN PRODUCTION [J]. NATURE, 1992, 360 (6405) : 672 - 674

[3] GENE DOSE OF APOLIPOPROTEIN-E TYPE-4 ALLELE AND THE RISK OF ALZHEIMERS-DISEASE IN LATE-ONSET FAMILIES [J]. SCIENCE, 1993, 261 (5123) : 921 - 923

[4] Gravina S. A., 1994, Society for Neuroscience Abstracts, V20, P437

[5] AMYLOID BETA-PEPTIDE IS PRODUCED BY CULTURED-CELLS DURING NORMAL METABOLISM [J]. NATURE, 1992, 359 (6393) : 322 - 325

[6] VISUALIZATION OF A-BETA-42(43) AND A-BETA-40 IN SENILE PLAQUES WITH END-SPECIFIC A-BETA MONOCLONALS - EVIDENCE THAT AN INITIALLY DEPOSITED SPECIES IS A-BETA-42(43) [J]. NEURON, 1994, 13 (01) : 45 - 53

[7] AMYLOID-BETA PROTEIN (A-BETA) DEPOSITION - A-BETA-42(43) PRECEDES A-BETA-40 IN DOWN-SYNDROME [J]. ANNALS OF NEUROLOGY, 1995, 37 (03) : 294 - 299

[8] AMYLOID-ASSOCIATED PROTEINS ALPHA(1)-ANTICHYMOTRYPSIN AND APOLIPOPROTEIN-E PROMOTE ASSEMBLY OF ALZHEIMER BETA-PROTEIN INTO FILAMENTS [J]. NATURE, 1994, 372 (6501) : 92 - 94

[9] PEPTIDE COMPOSITIONS OF THE CEREBROVASCULAR AND SENILE PLAQUE CORE AMYLOID DEPOSITS OF ALZHEIMERS-DISEASE [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1993, 301 (01) : 41 - 52

[10] ROHER AE, 1993, J BIOL CHEM, V268, P3072

[1] RELEASE OF EXCESS AMYLOID BETA-PROTEIN FROM A MUTANT AMYLOID BETA-PROTEIN PRECURSOR [J]. SCIENCE, 1993, 259 (5094) : 514 - 516

[2] MUTATION OF THE BETA-AMYLOID PRECURSOR PROTEIN IN FAMILIAL ALZHEIMERS-DISEASE INCREASES BETA-PROTEIN PRODUCTION [J]. NATURE, 1992, 360 (6405) : 672 - 674

[3] GENE DOSE OF APOLIPOPROTEIN-E TYPE-4 ALLELE AND THE RISK OF ALZHEIMERS-DISEASE IN LATE-ONSET FAMILIES [J]. SCIENCE, 1993, 261 (5123) : 921 - 923

[4] Gravina S. A., 1994, Society for Neuroscience Abstracts, V20, P437

[5] AMYLOID BETA-PEPTIDE IS PRODUCED BY CULTURED-CELLS DURING NORMAL METABOLISM [J]. NATURE, 1992, 359 (6393) : 322 - 325

[6] VISUALIZATION OF A-BETA-42(43) AND A-BETA-40 IN SENILE PLAQUES WITH END-SPECIFIC A-BETA MONOCLONALS - EVIDENCE THAT AN INITIALLY DEPOSITED SPECIES IS A-BETA-42(43) [J]. NEURON, 1994, 13 (01) : 45 - 53

[7] AMYLOID-BETA PROTEIN (A-BETA) DEPOSITION - A-BETA-42(43) PRECEDES A-BETA-40 IN DOWN-SYNDROME [J]. ANNALS OF NEUROLOGY, 1995, 37 (03) : 294 - 299

[8] AMYLOID-ASSOCIATED PROTEINS ALPHA(1)-ANTICHYMOTRYPSIN AND APOLIPOPROTEIN-E PROMOTE ASSEMBLY OF ALZHEIMER BETA-PROTEIN INTO FILAMENTS [J]. NATURE, 1994, 372 (6501) : 92 - 94

[9] PEPTIDE COMPOSITIONS OF THE CEREBROVASCULAR AND SENILE PLAQUE CORE AMYLOID DEPOSITS OF ALZHEIMERS-DISEASE [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1993, 301 (01) : 41 - 52

[10] ROHER AE, 1993, J BIOL CHEM, V268, P3072