CA-2+-DEPENDENT CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FROM RABBIT LUNG

被引：26

作者：

SHARMA, RK

WIRCH, E

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 91卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0006-291X(79)90623-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Studies are presented which demonstrate that rabbit lung contains both Ca2+-activated cyclic nucleotide phosphodiesterase and calmodulin activity. The Ca2+-activatable cyclic nucleotide phosphodiesterase is different from the common type in that it contains tightly bound calmodulin. The bound calmodulin is not dissociated from the enzyme even in very low concentrations of Ca2+ after DEAE-cellulose and Sephadex G-200 column chromatography. © 1979.

引用

页码：338 / 344

页数：7

共 13 条

[1]

BERGSTRAND H, 1978, J BIOL CHEM, V253, P1881

[2] PARTIAL-PURIFICATION AND CHARACTERIZATION OF ADENOSINE-3' AND GUANOSINE-3',5'-MONOPHOSPHATE PHOSPHODIESTERASES FROM HUMAN LUNG-TISSUE [J].