RESULTS OF MULTIMODAL THERAPY IN EWINGS-SARCOMA - A RETROSPECTIVE ANALYSIS OF 20 PATIENTS

被引：2

作者：

BENARUSH, M

KUTEN, A

PEREZNAHUM, M

COHEN, Y

BIALIK, V

机构：

[1] NO ISRAEL ONCOL CTR,RAMBAM MED CTR,RADIOTHERAPY UNIT,IL-35254 HAIFA,ISRAEL

[2] RAMBAM MED CTR,DEPT ORTHOPED,HAIFA,ISRAEL

[3] TECHNION ISRAEL INST TECHNOL,FAC MED,HAIFA,ISRAEL

[4] BEN GURION UNIV NEGEV,FAC MED,SOROKA MED CTR,DEPT ONCOL,IL-84105 BEER SHEVA,ISRAEL

[5] NO ISRAEL ONCOL CTR,PEDIAT ONCOL UNIT,IL-35254 HAIFA,ISRAEL

来源：

JOURNAL OF SURGICAL ONCOLOGY | 1991年 / 48卷 / 01期

关键词：

VACA CHEMOTHERAPY; SURGERY; RADIOTHERAPY; CENTRAL SKELETAL LESIONS; PERIPHERAL SKELETAL LESIONS;

D O I：

10.1002/jso.2930480110

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A retrospective analysis was performed of 20 patients with Ewing's sarcoma treated by combined modality therapy, consisting of surgery, radiotherapy, and chemotherapy. Fourteen patients (70%) achieved complete remission and 5 patients (25%) were in partial remission at the end of treatment. One patient (5%) failed to respond to combined modality therapy. The overall 5 year actuarial survival was 64% and the disease free survival, 55%. Persistent or recurrent disease occurred in 8 patients (40%); one of them was salvaged by surgery and chemotherapy. Site and extent of primary lesion were prognosticators of patients' outcome. One patient developed radiation-related-sequelae. The efficacy of aggressive management consisting of wide surgery, radiotherapy and intermittent high dose chemotherapy is discussed.

引用

页码：51 / 55

页数：5

共 21 条

[1]

[Anonymous], 1921, PROC N PATHOL SOC

[2]

BURGET EO, 1988, ASCO, V7, P1023

[3]

CHAN RC, 1979, CANCER-AM CANCER SOC, V43, P1001, DOI 10.1002/1097-0142(197903)43:3<1001::AID-CNCR2820430332>3.0.CO

[4]

2-P

[5]

COHEN Y, 1984, COMPUTERS RADIOLOGY, P207

[6]

ENNEKING WF, 1980, CLIN ORTHOP RELAT R, V153, P106

[7]

GLAUBIGER DL, 1980, CANCER, V45, P2213, DOI 10.1002/1097-0142(19800415)45:8<2213::AID-CNCR2820450834>3.0.CO

[8]

2-L

[9] THERAPY FOR LOCALIZED EWINGS-SARCOMA OF BONE [J].

HAYES, FA ;

THOMPSON, EI ;

MEYER, WH ;

KUN, L ;

PARHAM, D ;

RAO, B ;

KUMAR, M ;

HANCOCK, M ;

PARVEY, L ;

MAGILL, L ;

HUSTU, HO .

JOURNAL OF CLINICAL ONCOLOGY, 1989, 7 (02) :208-213

[10] LONG-TERM SURVIVAL IN PATIENTS WITH EWINGS-SARCOMA RELAPSING AFTER COMPLETING THERAPY [J].

HAYES, FA ;

THOMPSON, EI ;

KUMAR, M ;

HUSTU, HO .

MEDICAL AND PEDIATRIC ONCOLOGY, 1987, 15 (05) :254-256

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