CIS-DIHYDROCATECHOLS AS PRECURSORS TO HIGHLY OXYGENATED TROPONOIDS - A FULLY REGIOCONTROLLED SYNTHESIS OF 3,4-DIMETHOXY-ALPHA-TROPOLONE

被引：20

作者：

BANWELL, MG ^{[1
]}

CORBETT, M ^{[1
]}

MACKAY, MF ^{[1
]}

RICHARDS, SL ^{[1
]}

机构：

[1] LA TROBE UNIV,DEPT CHEM,BUNDOORA,VIC 3083,AUSTRALIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 11期

关键词：

D O I：

10.1039/p19920001329

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The highly oxygenated alpha-tropolone antibiotic 3,4-dimethoxy-alpha-tropolone 3 has been synthesized in a fully regiocontrolled manner from commercially available cis-1,2-dihydrocatechol 5. Demethylation of 3,4-dimethoxy-alpha-tropolone 3 produced the potent antitumour agent 3,4-dihydroxy-alpha-tropolone 4.

引用

页码：1329 / 1334

页数：6

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