THE DOWNSTREAM REGULATORY SEQUENCE OF THE ADENOVIRUS TYPE-2 MAJOR LATE PROMOTER IS FUNCTIONALLY REDUNDANT

被引：5

作者：

LI, XC ^{[1
]}

HUANG, WL ^{[1
]}

FLINT, SJ ^{[1
]}

机构：

[1] PRINCETON UNIV,DEPT MOLEC BIOL,PRINCETON,NJ 08544

来源：

JOURNAL OF VIROLOGY | 1992年 / 66卷 / 09期

关键词：

D O I：

10.1128/JVI.66.9.5685-5690.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Mutagenesis of promoter sequences and oligonucleotide competition assays have been used to demonstrate that late-phase-specific stimulation of the adenovirus type 2 major late promoter is mediated by functionally redundant elements located between positions +75 and +125. These octamer motif-related sequences are recognized by multiple factors.

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页码：5685 / 5690

页数：6

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共 33 条

[1] OVERLAPPING OCTAMER AND TAATGARAT MOTIFS IN THE VF65-RESPONSE ELEMENTS IN HERPES-SIMPLEX VIRUS IMMEDIATE-EARLY PROMOTERS REPRESENT INDEPENDENT BINDING-SITES FOR CELLULAR NUCLEAR FACTOR-III [J].

APRHYS, CMJ ;

CIUFO, DM ;

ONEILL, EA ;

KELLY, TJ ;

HAYWARD, GS .

JOURNAL OF VIROLOGY, 1989, 63 (06) :2798-2812

[2] OBP100 BINDS REMARKABLY DEGENERATE OCTAMER MOTIFS THROUGH SPECIFIC INTERACTIONS WITH FLANKING SEQUENCES [J].

BAUMRUKER, T ;

STURM, R ;

HERR, W .

GENES & DEVELOPMENT, 1988, 2 (11) :1400-1413

[3] DNA-BINDING PROPERTIES OF AN ADENOVIRUS 289R-E1A PROTEIN [J].

CHATTERJEE, PK ;

BRUNER, M ;

FLINT, SJ ;

HARTER, ML .

EMBO JOURNAL, 1988, 7 (03) :835-841

[4] PURIFICATION AND CHARACTERIZATION OF OTF-1, A TRANSCRIPTION FACTOR REGULATING CELL-CYCLE EXPRESSION OF A HUMAN HISTONE H2B GENE [J].

FLETCHER, C ;

HEINTZ, N ;

ROEDER, RG .

CELL, 1987, 51 (05) :773-781

[5] A HERPESVIRUS TRANS-ACTIVATING PROTEIN INTERACTS WITH TRANSCRIPTION FACTOR OTF-1 AND OTHER CELLULAR PROTEINS [J].

GERSTER, T ;

ROEDER, RG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (17) :6347-6351

[6] AN ADENOVIRUS EARLY REGION-4 GENE-PRODUCT IS REQUIRED FOR INDUCTION OF THE INFECTION-SPECIFIC FORM OF CELLULAR E2F ACTIVITY [J].

HARDY, S ;

ENGEL, DA ;

SHENK, T .

GENES & DEVELOPMENT, 1989, 3 (07) :1062-1074

[7] THE ADENOVIRUS EARLY REGION-4 OPEN READING FRAME 6/7 PROTEIN REGULATES THE DNA-BINDING ACTIVITY OF THE CELLULAR TRANSCRIPTION FACTOR, E2F, THROUGH A DIRECT COMPLEX [J].

HUANG, MM ;

HEARING, P .

GENES & DEVELOPMENT, 1989, 3 (11) :1699-1710

[8] REPLICATION-INDUCED STIMULATION OF THE MAJOR LATE PROMOTER OF ADENOVIRUS IS CORRELATED TO THE BINDING OF A FACTOR TO SEQUENCES IN THE 1ST INTRON [J].

JANSENDURR, P ;

BOEUF, H ;

KEDINGER, C .

NUCLEIC ACIDS RESEARCH, 1988, 16 (09) :3771-3786

[9] REPLICATION-DEPENDENT ACTIVATION OF THE ADENOVIRUS MAJOR LATE PROMOTER IS MEDIATED BY THE INCREASED BINDING OF A TRANSCRIPTION FACTOR TO SEQUENCES IN THE 1ST INTRON [J].

JANSENDURR, P ;

MONDESERT, G ;

KEDINGER, C .

JOURNAL OF VIROLOGY, 1989, 63 (12) :5124-5132

[10] ANATOMY OF AN UNUSUAL RNA POLYMERASE-II PROMOTER CONTAINING A DOWNSTREAM TATA ELEMENT [J].

KASAI, Y ;

CHEN, HJ ;

FLINT, SJ .

MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (06) :2884-2897

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