MULTICENTER COMPARISON OF IN-VITRO ACTIVITIES OF FK-037, CEFEPIME, CEFTRIAXONE, CEFTAZIDIME, AND CEFUROXIME

被引：41

作者：

WASHINGTON, JA

JONES, RN

GERLACH, EH

MURRAY, PR

ALLEN, SD

KNAPP, CC

机构：

[1] UNIV IOWA HOSP & CLIN,IOWA CITY,IA 52242

[2] ST FRANCIS REG MED CTR,WICHITA,KS 67214

[3] WASHINGTON UNIV,MED CTR,ST LOUIS,MO 63130

[4] INDIANA UNIV,MED CTR,INDIANAPOLIS,IN 46223

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 08期

关键词：

D O I：

10.1128/AAC.37.8.1696

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In a multicenter study, the MICs of FK-037 for 90% of the strains tested (MIC90s) were less-than-or-equal-to 1 mug/ml for members of the family Enterobacteriaceae other than Citrobacter freundii, Enterobacter spp., and Serratia marcescens. Activity against Pseudomonas aeruginosa was variable, with a MIC50 and a MIC90 of 4 and 32 mug/ml, respectively. Relative to cefepime, however, FK-037 was less active against ceftazidime-resistant isolates of Enterobacter cloacae. The MIC90 of FK-037 for methicillin-resistant staphylococci was > 16 mug/ml.

引用

页码：1696 / 1700

页数：5

共 16 条

[1]

ENG RH, 1992, 32ND INT C ANT AG CH, P177

[2] INVITRO AND INVIVO ANTIBACTERIAL ACTIVITIES OF FK037, A NOVEL PARENTERAL BROAD-SPECTRUM CEPHALOSPORIN [J].