A STUDY OF TOTAL THERAPY OF ACUTE LYMPHOCYTIC LEUKEMIA IN CHILDREN

被引：109

作者：

GEORGE, P

HERNANDEZ, K

HUSTU, O

BORELLA, L

HOLTON, C

PINKEL, D

机构：

[1] St. Jude Children's Research Hospital, Memphis, TN

[2] Department of Pediatrics, University of Tennessee College of Medicine, Memphis, TN

来源：

JOURNAL OF PEDIATRICS | 1968年 / 72卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0022-3476(68)80217-3

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A study was designed to test the hypothesis that, following induction of remission and an intensive short-term, high-dosage phase of treatment, continuous maintenance chemotherapy with the use of a combination of 4 antileukemic agents concurrently in conjunction with radiotherapy to the entire craniospinal axis would produce prolonged complete remission in patients with previously untreated acute lymphocytic leukemia. The intensive systemic administration of antileukemic agents resulted in longer complete remissions than described in other studies, and survival was at least equal to that obtained with sequential use of these agents. © 1968 The C. V. Mosby Company.

引用

页码：399 / +

页数：1

共 22 条

[1] BISEL HF, 1956, BLOOD, V11, P676
[2] BRUBAKER CA, 1963, BLOOD, V22, P820
[3] EVANS AE, 1964, CANCER, V17, P256, DOI 10.1002/1097-0142(196402)17:2<256::AID-CNCR2820170216>3.0.CO
[4] 2-3
[5] TEMPORARY REMISSIONS IN ACUTE LEUKEMIA IN CHILDREN PRODUCED BY FOLIC ACID ANTAGONIST, 4-AMINOPTEROYL-GLUTAMIC ACID (AMINOPTERIN)
FARBER, S
DIAMOND, LK
MERCER, RD
SYLVESTER, RF
WOLFF, JA
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1948, 238 (23) : 787 - 793
[6] CHEMOTHERAPY OF ACUTE LEUKEMIA IN CHILDHOOD - COMPARISON OF CYCLOPHOSPHAMIDE AND MERCAPTOPURINE
FERNBACH, DJ
GRIFFITH, KM
HAGGARD, ME
HOLCOMB, TM
SUTOW, WW
VIETTI, TJ
WINDMILL.J
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1966, 275 (09) : 451 - &
[7] STUDIES OF SEQUENTIAL AND COMBINATION ANTIMETABOLITE THERAPY IN ACUTE LEUKEMIA - 6-MERCAPTOPURINE AND METHOTREXATE
FREI, E
TRAGGIS, DG
GENDEL, BR
HOLLAND, JF
TAYLOR, R
EBAUGH, F
HAURANI, F
HAYES, DM
SODEE, DB
RUNDLES, RW
WOLMAN, IJ
JAMES, GW
GEHAN, E
SCHROEDER, LR
FREIREICH, EJ
ROTHBERG, H
PINKEL, D
HOOGSTRATEN, B
SPURR, CL
SELWARY, O
COOPER, T
[J]. BLOOD, 1961, 18 (04) : 431 - &
[8] FREIREICH E. J., 1964, PROC AMER ASSOC CANCER RES, V5, P20
[9] EFFECTIVENESS OF COMBINATIONS OF ANTILEUKEMIC AGENTS IN INDUCING AND MAINTAINING REMISSION IN CHILDREN WITH ACUTE LEUKEMIA
FREI, E
KARON, M
LEVIN, RH
FREIREICH, EJ
TAYLOR, RJ
HANANIAN, J
SELAWRY, O
HOLLAND, JF
HOOGSTRATEN, B
WOLMAN, IJ
ABIR, E
SAWITSKY, A
LEE, S
MILLS, SD
BURGERT, EO
SPURR, CL
PATTERSON, RB
EBAUGH, FG
JAMES, GW
MOON, JH
[J]. BLOOD-THE JOURNAL OF HEMATOLOGY, 1965, 26 (05): : 642 - +
[10] FREIREICH EJ, 1963, BLOOD, V21, P699

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