X-MAPPING IN MAN - EVIDENCE AGAINST MEASURABLE LINKAGE BETWEEN ANHIDROTIC ECTODERMAL DYSPLASIA AND G6PD DEFICIENCY

被引：8

作者：

FILIPPI, G

RINALDI, A

CRISPONI, G

DANIELS, GL

SINISCALCO, M

机构：

[1] SLOAN KETTERING INST CANC RES,425 E 68TH ST,NEW YORK,NY 10021

[2] UNIV TRIESTE,IST GENET MED,I-34127 TRIESTE,ITALY

[3] UNIV ROME,CNR,CTR GENET EVOLUZ,I-00100 ROME,ITALY

[4] UNIV CAGLIARI,IST PUERICULTURA,I-09100 CAGLIARI,ITALY

[5] MRC,BLOOD GRP UNIT,LONDON NW1,ENGLAND

来源：

JOURNAL OF MEDICAL GENETICS | 1979年 / 16卷 / 03期

关键词：

D O I：

10.1136/jmg.16.3.223

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A Sardinian kindred segregating for X-linked anhidrotic ectodermal dysplasia (AED), glucose-6-phosphate dehydrogenase (G6PD) deficiency of Mediterranean type, and Xg(a) blood antigen provides evidence against a measurable linkage between the loci for AED and G6PD. Moreover, from the segregation of the combined phenotypes in four scorable sons from two triple heterozygotes with phase known, it seems highly probable that the AED locus is nearer to the centromere than is the G6PD locus.

引用

页码：223 / 224

页数：2

共 6 条

[1]

Brown J A, 1976, Birth Defects Orig Artic Ser, V12, P54

[2]

GALL JC, 1965, AM J HUM GENET, V17, P359

[3] X-CHROMOSOME INACTIVATION IN X-LINKED HYPOHIDROTIC ECTODERMAL DYSPLASIA [J].

PASSARGE, E ;

FRIES, E .

NATURE-NEW BIOLOGY, 1973, 245 (141) :58-59

[4]

RACE RR, 1975, BLOOD GROUPS MAN, P603

[5]

RINALDI A, 1976, AM J HUM GENET, V28, P496

[6] FAILURE TO DETECT LINKAGE BETWEEN XG AND OTHER X-BORNE LOCI IN SARDINIANS [J].

SINISCALCO, M ;

FILIPPI, G ;

LATTE, B ;

PIOMELLI, S ;

RATTAZZI, M ;

GAVIN, J ;

SANGER, R ;

RACE, RR .

ANNALS OF HUMAN GENETICS, 1966, 29 :231-+

← 1 →