MORPHICEPTIN (NH4-TYR-PRO-PHE-PRO-CONH2) - A POTENT AND SPECIFIC AGONIST FOR MORPHINE (MU) RECEPTORS

被引：366

作者：

CHANG, KJ ^{[1
]}

KILLIAN, A ^{[1
]}

HAZUM, E ^{[1
]}

CUATRECASAS, P ^{[1
]}

CHANG, JK ^{[1
]}

机构：

[1] PENINSULA LABS,SAN CARLOS,CA 94070

来源：

SCIENCE | 1981年 / 212卷 / 4490期

关键词：

D O I：

10.1126/science.6259732

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

收藏

页码：75 / 77

页数：3

相关论文

共 19 条

[1] INTERACTION OF LIGANDS WITH OPIATE RECEPTORS OF BRAIN MEMBRANES - REGULATION BY IONS AND NUCLEOTIDES
BLUME, AJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (04) : 1713 - 1717
[2] MATERIAL WITH OPIOID ACTIVITY IN BOVINE-MILK AND MILK-PRODUCTS
BRANTL, V
TESCHEMACHER, H
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1979, 306 (03) : 301 - 304
[3] CHANG K, UNPUBLISHED
[4] POSSIBLE ROLE OF DISTINCT MORPHINE AND ENKEPHALIN RECEPTORS IN MEDIATING ACTIONS OF BENZOMORPHAN DRUGS (PUTATIVE-KAPPA AND SIGMA-AGONISTS)
CHANG, KJ
HAZUM, E
CUATRECASAS, P
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (08): : 4469 - 4473
[5] CHANG KJ, 1979, J BIOL CHEM, V254, P2610
[6] CHANG KJ, 1979, MOL PHARMACOL, V16, P91
[7] CHANG KJ, MOL PHARMACOL
[8] OPIATE RECEPTOR-BINDING AFFECTED DIFFERENTIALLY BY OPIATES AND OPIOID PEPTIDES
CHILDERS, SR
CREESE, I
SNOWMAN, AM
SNYDER, SH
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1979, 55 (01) : 11 - 18
[9] GUANINE NUCLEOTIDES DIFFERENTIATE AGONIST AND ANTAGONIST INTERACTIONS WITH OPIATE RECEPTORS
CHILDERS, SR
SNYDER, SH
[J]. LIFE SCIENCES, 1978, 23 (07) : 759 - 761
[10] MULTIPLE OPIATE RECEPTOR-SITES ON PRIMARY AFFERENT-FIBERS
FIELDS, HL
EMSON, PC
LEIGH, BK
GILBERT, RFT
IVERSEN, LL
[J]. NATURE, 1980, 284 (5754) : 351 - 353