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THE SEVERITY OF POSTISCHEMIC HYPOPERFUSION INCREASES WITH DURATION OF CEREBRAL-ISCHEMIA IN RATS

被引：20
作者：
KARLSSON, BR
GROGAARD, B
GERDIN, B
STEEN, PA
机构：
[1] UNIV OSLO,ULLEVAL HOSP,DEPT SURG,N-0407 OSLO 4,NORWAY
[2] AKAD SJUKHUSET,DEPT SURG,UPPSALA,SWEDEN
来源：
ACTA ANAESTHESIOLOGICA SCANDINAVICA | 1994年 / 38卷 / 03期
关键词：
CEREBRAL BLOOD FLOW; CEREBRAL ISCHEMIA; POSTISCHEMIC HYPOPERFUSION;
D O I：
10.1111/j.1399-6576.1994.tb03883.x
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Regional cerebral blood flow was studied after a period of hypotensive bilateral carotid occlusion in rats. As other studies have found, we confirm that 15 min of ischemia caused an initial brief hyperemic episode followed by severe hypoperfusion in all areas. With varying duration of ischemia from 5 to 10, 15 and 20 min, the median cerebral blood flow 60 min postischemia was 79%, 46%, 48% and 34% of control, respectively. Thus the degree of postischemic hypoperfusion increased significantly with the duration of ischemia.
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页码：248 / 253
页数：6
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