INHIBITION OF THYMIDYLATE SYNTHETASE BY 5-ALKYNYL-2'-DEOXYURIDYLATES

被引：38

作者：

BARR, PJ

NOLAN, PA

SANTI, DV

ROBINS, MJ

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

[3] UNIV ALBERTA,DEPT CHEM,EDMONTON T6G 2G2,ALBERTA,CANADA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1981年 / 24卷 / 12期

关键词：

D O I：

10.1021/jm00144a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：1385 / 1388

页数：4

相关论文

共 17 条

[1] SUICIDE ENZYME INACTIVATORS
ABELES, RH
MAYCOCK, AL
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1976, 9 (09) : 313 - 319
[2] BOBEK M, 1978, CHEM BIOL NUCLEOSIDE, P135
[3] ANTIVIRAL ACTION AND CELLULAR TOXICITY OF 4 THYMIDINE ANALOGS - 5-ETHYL-DEOXYURIDINE, 5-VINYL-DEOXYURIDINE, 5-PROPYL-DEOXYURIDINE, AND 5-ALLYL-2'-DEOXYURIDINE
CHENG, YC
DOMIN, BA
SHARMA, RA
BOBEK, M
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1976, 10 (01) : 119 - 122
[4] THYMIDYLATE SYNTHETASE - TARGET ENZYME IN CANCER CHEMOTHERAPY
DANENBERG, PV
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 473 (02) : 73 - 92
[5] DECLERCQ E, 1981, MOL PHARMACOL, V19, P321
[6] SMALL-SCALE PREPARATION OF 5'-NUCLEOTIDES AND ANALOGS BY CARROT PHOSPHOTRANSFERASE
HARVEY, CL
CLERICUZIO, EM
NUSSBAUM, AL
[J]. ANALYTICAL BIOCHEMISTRY, 1970, 36 (02) : 413 - +
[7] KALMAN TI, 1979, DRUG ACTION DESIGN M, P75
[8] POGOLOTTI AL, 1977, BIOORG CHEM, V1, P277
[9] RANDO RR, 1977, METHODS ENZYMOL, V46, P164
[10] NUCLEIC-ACID RELATED-COMPOUNDS .31. SMOOTH AND EFFICIENT PALLADIUM-COPPER CATALYZED COUPLING OF TERMINAL ALKYNES WITH 5-IODOURACIL NUCLEOSIDES
ROBINS, MJ
BARR, PJ
[J]. TETRAHEDRON LETTERS, 1981, 22 (05) : 421 - 424