CYCLODESULFURIZATION OF THIO-COMPOUNDS .17. SYNTHESIS OF SOME NOVEL 2-SUBSTITUTED AMINO-3,4-DIHYDRO-5H-1,3,4-BENZOTRIAZEPIN-5-ONES BY CYCLODE-SULFURIZATION OF THIOSEMICARBAZIDES WITH DICYCLOHEXYLCARBODIIMIDE (DCCD)

被引：13

作者：

OMAR, AMME ^{[1
]}

ASHOUR, FA ^{[1
]}

BOURDAIS, J ^{[1
]}

机构：

[1] UNIV PARIS SUD,CTR ORSAY,CHIM HETEROCYCL & ORGANOMET LAB,F-91400 ORSAY,FRANCE

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1979年 / 16卷 / 07期

关键词：

D O I：

10.1002/jhet.5570160729

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple method for the synthesis of a novel series of 2‐substituted amino‐3,4‐dihydro‐5H‐1,3,4‐benzotriazepin‐5‐ones (11–16) has been established through two routes. The first involving the cyelodesulfurization of the thiosemicarbazides (3–8) with DCCD and the second reacting mixtures of the acid hydrazide 1 with a variety of the isothiocyanates 2 and DCCD. The structure of the cyclized products was confirmed by nmr and mass spectra. Copyright © 1979 Journal of Heterocyclic Chemistry

引用

页码：1435 / 1438

页数：4