BREAST-MILK CAN MEDIATE CHEMICAL IMPRINTING - BENZPYRENE EXPOSURE DURING LACTATION REDUCES THE THYMIC GLUCOCORTICOID RECEPTOR DENSITY OF THE OFFSPRING

被引：5

作者：

CSABA, G

INCZEFIGONDA, A

机构：

来源：

GENERAL PHARMACOLOGY | 1994年 / 25卷 / 03期

关键词：

D O I：

10.1016/0306-3623(94)90221-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. prolonged benzpyrene treatment during lactation reduced the number of glucocorticoid receptors of offspring in adulthood significantly without altering the receptor affinity. 2. Dexamethasone treatment identical to benzpyrene exposure had no effect either on receptor number or affinity. 3. The results of the present investigations draw attention to the possible way of receptor alteration via breastmilk.

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页码：603 / 606

页数：4

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