HPLC SEPARATION OF ENANTIOMERS OF AMINO-ACIDS AND AMINO-ALCOHOLS ON IONICALLY BONDED CHIRAL STATIONARY PHASES CONSISTING OF CYANURIC CHLORIDE WITH AMINO-ACID AND DIALKYLAMINE SUBSTITUENTS

被引：15

作者：

CHEN, CC ^{[1
]}

LIN, CE ^{[1
]}

机构：

[1] NATL TAIWAN UNIV,DEPT CHEM,TAIPEI 10764,TAIWAN

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 1995年 / 33卷 / 05期

关键词：

D O I：

10.1093/chromsci/33.5.229

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Six silica-based, ionically bonded, chiral stationary phases consisting of cyanuric chloride with substituents (an L-amino acid and a dialkylamine) are prepared. These phases allow the recognition and separation of enantiomers of both methyl esters of N-(3,5-dinitrobenzoyl)-amino acids and N-(3,5-dinitrobenzoyl)-amino alcohols by high-performance liquid chromatography. Generally, amino acids are separated more effectively than amino alcohols. A mechanism for chiral recognition with a liquid chromatograph is discussed. The present results provide further evidence to support the previously proposed model of chiral recognition. © 1995, Oxford University Press.

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页码：229 / 235

页数：7

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